磁共振成像（MRI）图像中的小病变对于多种疾病的临床诊断至关重要。但是，MRI质量很容易被各种噪声降解，这可以极大地影响小病变的诊断准确性。尽管已经提出了一些用于降级MR图像的方法，但缺乏提高特定于任务的降级方法来提高小病变的诊断信心。在这项工作中，我们建议通过体素杂种残留MLP-CNN模型来降低具有小病变的三维（3D）MR图像。我们结合了基本的深度学习体系结构MLP和CNN，以获得适当的固有偏差，以通过添加残差连接来利用远距离信息，以使图像降低并整合MLP和CNN中的每个输出层。我们在720 T2-Flair脑图像上评估了所提出的方法，其在不同的噪声水平下具有较小的病变。结果表明，与最先进的方法相比，在定量和视觉评估中，我们的方法在测试数据集上具有优势。此外，两名经验丰富的放射科医生同意，在中等和高噪声水平下，我们的方法在恢复小病变和整体图像质量方面优于其他方法。我们的方法的实现可在https://github.com/laowangbobo/Residual_MLP_CNN_MIXER上获得。

A further understanding of cause and effect within observational data is critical across many domains, such as economics, health care, public policy, web mining, online advertising, and marketing campaigns. Although significant advances have been made to overcome the challenges in causal effect estimation with observational data, such as missing counterfactual outcomes and selection bias between treatment and control groups, the existing methods mainly focus on source-specific and stationary observational data. Such learning strategies assume that all observational data are already available during the training phase and from only one source. This practical concern of accessibility is ubiquitous in various academic and industrial applications. That's what it boiled down to: in the era of big data, we face new challenges in causal inference with observational data, i.e., the extensibility for incrementally available observational data, the adaptability for extra domain adaptation problem except for the imbalance between treatment and control groups, and the accessibility for an enormous amount of data. In this position paper, we formally define the problem of continual treatment effect estimation, describe its research challenges, and then present possible solutions to this problem. Moreover, we will discuss future research directions on this topic.

The growing interest in intelligent services and privacy protection for mobile devices has given rise to the widespread application of federated learning in Multi-access Edge Computing (MEC). Diverse user behaviors call for personalized services with heterogeneous Machine Learning (ML) models on different devices. Federated Multi-task Learning (FMTL) is proposed to train related but personalized ML models for different devices, whereas previous works suffer from excessive communication overhead during training and neglect the model heterogeneity among devices in MEC. Introducing knowledge distillation into FMTL can simultaneously enable efficient communication and model heterogeneity among clients, whereas existing methods rely on a public dataset, which is impractical in reality. To tackle this dilemma, Federated MultI-task Distillation for Multi-access Edge CompuTing (FedICT) is proposed. FedICT direct local-global knowledge aloof during bi-directional distillation processes between clients and the server, aiming to enable multi-task clients while alleviating client drift derived from divergent optimization directions of client-side local models. Specifically, FedICT includes Federated Prior Knowledge Distillation (FPKD) and Local Knowledge Adjustment (LKA). FPKD is proposed to reinforce the clients' fitting of local data by introducing prior knowledge of local data distributions. Moreover, LKA is proposed to correct the distillation loss of the server, making the transferred local knowledge better match the generalized representation. Experiments on three datasets show that FedICT significantly outperforms all compared benchmarks in various data heterogeneous and model architecture settings, achieving improved accuracy with less than 1.2% training communication overhead compared with FedAvg and no more than 75% training communication round compared with FedGKT.

Reinforcement learning (RL) is one of the most important branches of AI. Due to its capacity for self-adaption and decision-making in dynamic environments, reinforcement learning has been widely applied in multiple areas, such as healthcare, data markets, autonomous driving, and robotics. However, some of these applications and systems have been shown to be vulnerable to security or privacy attacks, resulting in unreliable or unstable services. A large number of studies have focused on these security and privacy problems in reinforcement learning. However, few surveys have provided a systematic review and comparison of existing problems and state-of-the-art solutions to keep up with the pace of emerging threats. Accordingly, we herein present such a comprehensive review to explain and summarize the challenges associated with security and privacy in reinforcement learning from a new perspective, namely that of the Markov Decision Process (MDP). In this survey, we first introduce the key concepts related to this area. Next, we cover the security and privacy issues linked to the state, action, environment, and reward function of the MDP process, respectively. We further highlight the special characteristics of security and privacy methodologies related to reinforcement learning. Finally, we discuss the possible future research directions within this area.

Denoising Diffusion Probabilistic Models (DDPMs) are emerging in text-to-speech (TTS) synthesis because of their strong capability of generating high-fidelity samples. However, their iterative refinement process in high-dimensional data space results in slow inference speed, which restricts their application in real-time systems. Previous works have explored speeding up by minimizing the number of inference steps but at the cost of sample quality. In this work, to improve the inference speed for DDPM-based TTS model while achieving high sample quality, we propose ResGrad, a lightweight diffusion model which learns to refine the output spectrogram of an existing TTS model (e.g., FastSpeech 2) by predicting the residual between the model output and the corresponding ground-truth speech. ResGrad has several advantages: 1) Compare with other acceleration methods for DDPM which need to synthesize speech from scratch, ResGrad reduces the complexity of task by changing the generation target from ground-truth mel-spectrogram to the residual, resulting into a more lightweight model and thus a smaller real-time factor. 2) ResGrad is employed in the inference process of the existing TTS model in a plug-and-play way, without re-training this model. We verify ResGrad on the single-speaker dataset LJSpeech and two more challenging datasets with multiple speakers (LibriTTS) and high sampling rate (VCTK). Experimental results show that in comparison with other speed-up methods of DDPMs: 1) ResGrad achieves better sample quality with the same inference speed measured by real-time factor; 2) with similar speech quality, ResGrad synthesizes speech faster than baseline methods by more than 10 times. Audio samples are available at https://resgrad1.github.io/.

Face manipulation detection has been receiving a lot of attention for the reliability and security of the face images. Recent studies focus on using auxiliary information or prior knowledge to capture robust manipulation traces, which are shown to be promising. As one of the important face features, the face depth map, which has shown to be effective in other areas such as the face recognition or face detection, is unfortunately paid little attention to in literature for detecting the manipulated face images. In this paper, we explore the possibility of incorporating the face depth map as auxiliary information to tackle the problem of face manipulation detection in real world applications. To this end, we first propose a Face Depth Map Transformer (FDMT) to estimate the face depth map patch by patch from a RGB face image, which is able to capture the local depth anomaly created due to manipulation. The estimated face depth map is then considered as auxiliary information to be integrated with the backbone features using a Multi-head Depth Attention (MDA) mechanism that is newly designed. Various experiments demonstrate the advantage of our proposed method for face manipulation detection.

The development of deep learning models in medical image analysis is majorly limited by the lack of large-sized and well-annotated datasets. Unsupervised learning does not require labels and is more suitable for solving medical image analysis problems. However, most of the current unsupervised learning methods need to be applied to large datasets. To make unsupervised learning applicable to small datasets, we proposed Swin MAE, which is a masked autoencoder with Swin Transformer as its backbone. Even on a dataset of only a few thousand medical images and without using any pre-trained models, Swin MAE is still able to learn useful semantic features purely from images. It can equal or even slightly outperform the supervised model obtained by Swin Transformer trained on ImageNet in terms of the transfer learning results of downstream tasks. The code will be publicly available soon.

In this paper, we study the \underline{R}obust \underline{o}ptimization for \underline{se}quence \underline{Net}worked \underline{s}ubmodular maximization (RoseNets) problem. We interweave the robust optimization with the sequence networked submodular maximization. The elements are connected by a directed acyclic graph and the objective function is not submodular on the elements but on the edges in the graph. Under such networked submodular scenario, the impact of removing an element from a sequence depends both on its position in the sequence and in the network. This makes the existing robust algorithms inapplicable. In this paper, we take the first step to study the RoseNets problem. We design a robust greedy algorithm, which is robust against the removal of an arbitrary subset of the selected elements. The approximation ratio of the algorithm depends both on the number of the removed elements and the network topology. We further conduct experiments on real applications of recommendation and link prediction. The experimental results demonstrate the effectiveness of the proposed algorithm.

In optimization-based approaches to inverse problems and to statistical estimation, it is common to augment the objective with a regularizer to address challenges associated with ill-posedness. The choice of a suitable regularizer is typically driven by prior domain information and computational considerations. Convex regularizers are attractive as they are endowed with certificates of optimality as well as the toolkit of convex analysis, but exhibit a computational scaling that makes them ill-suited beyond moderate-sized problem instances. On the other hand, nonconvex regularizers can often be deployed at scale, but do not enjoy the certification properties associated with convex regularizers. In this paper, we seek a systematic understanding of the power and the limitations of convex regularization by investigating the following questions: Given a distribution, what are the optimal regularizers, both convex and nonconvex, for data drawn from the distribution? What properties of a data source govern whether it is amenable to convex regularization? We address these questions for the class of continuous and positively homogenous regularizers for which convex and nonconvex regularizers correspond, respectively, to convex bodies and star bodies. By leveraging dual Brunn-Minkowski theory, we show that a radial function derived from a data distribution is the key quantity for identifying optimal regularizers and for assessing the amenability of a data source to convex regularization. Using tools such as $\Gamma$-convergence, we show that our results are robust in the sense that the optimal regularizers for a sample drawn from a distribution converge to their population counterparts as the sample size grows large. Finally, we give generalization guarantees that recover previous results for polyhedral regularizers (i.e., dictionary learning) and lead to new ones for semidefinite regularizers.

With the ever-growing model size and the limited availability of labeled training data, transfer learning has become an increasingly popular approach in many science and engineering domains. For classification problems, this work delves into the mystery of transfer learning through an intriguing phenomenon termed neural collapse (NC), where the last-layer features and classifiers of learned deep networks satisfy: (i) the within-class variability of the features collapses to zero, and (ii) the between-class feature means are maximally and equally separated. Through the lens of NC, our findings for transfer learning are the following: (i) when pre-training models, preventing intra-class variability collapse (to a certain extent) better preserves the intrinsic structures of the input data, so that it leads to better model transferability; (ii) when fine-tuning models on downstream tasks, obtaining features with more NC on downstream data results in better test accuracy on the given task. The above results not only demystify many widely used heuristics in model pre-training (e.g., data augmentation, projection head, self-supervised learning), but also leads to more efficient and principled fine-tuning method on downstream tasks that we demonstrate through extensive experimental results.